Prof Borody’s research interests have always been diverse and exciting, we now find ourselves at the forefront of emerging therapies for historical diseases. Neurological conditions such as Parkinson’s disease and Multiple Sclerosis (MS) and other conditions such as Coronary Heart Disease take on new meanings as we tackle them in our gastroenterological way. Coronary Heart Disease – Long has it been thought that Coronary Heart Disease is a result of poor lifestyle choices, but emerging evidence has implicated a bug may be responsible for the accumulation of ‘bad cholesterol’ in your arteries. This bug called Chlamydophila pneumoniae responsible for causing pneumonia and respiratory infections has been found in the cholesterol plaques of arteries, and the cholesterol is a result of inflammation in the presence of C. pneumoniae. Index cases treated with an antibiotic combination therapy have shown positive results and a clinical trial has been designed and submitted for review. This trial will be run by the cardiologists of Liverpool Hospital and Sydney Southwest Private hospital. For more information, please contact Margaux on 02 9713 4011 (press 3 for Research). Parkinson’s Disease has been considered a degenerative lifelong neurological disorder of which there is no cure and research into the cause of Parkinson’s disease has not been targeted as an infective cause. We have observed a positive benefit and reversal of Parkinson’s disease in an index case treated for chronic constipation. Unidentified bacteria may be responsible for a portion of those with Parkinson’s disease with constipation being a major symptom. A clinical trial is currently undergoing review that will look at the treatment of patients with Parkinson’s disease and chronic constipation with an antibiotic combination therapy. This trial will begin recruitment in the near future, for more information or if you would like to register your interest please contact the Research Department on 02 9713 4011 (press 3 for Research) Faecal Microbiota Transplantation – a transfer of stool from a healthy donor into a sick patient is a therapy offered here at the Centre for Digestive Diseases, with a positive benefit in the treatment of those with constipation, IBS, Clostridium Difficile infections and Inflammatory Bowel Diseases. We have been seeing a positive benefit in certain conditions such as Idiopathic Thrombocytopaenic Purpura (ITP) and atypical Multiple Sclerosis (MS) type conditions. These case reports have been submitted for presentation and we are hoping to dedicate more research in this field in the future.
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